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Event Title Spotlight on Evidence-based Synthesis Program
Event Description Safe and Effective Anticoagulation in the Outpatient Setting BACKGROUND Long term anticoagulation with Vitamin K antagonists (e.g., warfarin) has been shown to reduce major thromboembolic complications in patients with many common chronic conditions, including atrial fibrillation, history of deep vein thrombosis and pulmonary embolism, and mechanical heart valves. However, Vitamin K antagonists have a very narrow therapeutic window requiring frequent laboratory monitoring to ensure that patients are neither excessively anti-coagulated, which increases the risk for bleeding, or under anti-coagulated, which increases the risk for thromboembolism. Laboratory monitoring consists of measuring the blood’s tendency to clot with a test known as the International Normalized Ratio (INR), usually performed every 4-6 weeks. Dosage adjustments are then based on these results. OBJECTIVES The primary objectives of this systematic review were to: 1. Determine whether specialized anticoagulation clinics (ACC) are more effective and safer than care in non-specialized clinics (e.g., primary care clinics, physician offices) for management of long- term anticoagulation in adults; 2. Determine whether Patient Self Testing (PST), either alone or in combination with Patient Self Management (PSM), is more effective and safer than standard care; and 3. Identify the risk factors for serious bleeding in patients on chronic anticoagulant therapy.
 
  Date 9/27/2010
  Start time 12:00pm
  End time 1:00pm

 
  Presenters
 Name  About the presenter
Hanna Bloomfield, M.D.
Director, Center for Chronic Disease Outcomes Research Co-Chief, Section of General Internal Medicine/Primary Care, Minneapolis VAMC Staff Physician, Section of General Internal Medicine, Minneapolis VAMC Professor of Medicine,University of Minnesota School of Medicine
Presenting: Safe and Effective Anticoagulation in the Outpatient Setting
Brent Taylor, Ph.D.
Core Investigator, Center for Chronic Disease Outcomes Research Assistant Professor of Medicine, University of Minnesota Medical School Adjunct Assistant Professor of Epidemiology & Community Health, School of Public Health, University of Minnesota
Presenting: Safe and Effective Anticoagulation in the Outpatient Setting

 
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