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Instrument Summary for Compliance/Adherence
Please note that this section
is an archive and is no longer being updated.
1. Morisky Scale
Development: The Morisky Scale includes items originally constructed to measure
adherence with antihypertensive treatment. The item pool consisted of five items from a scale by Green et al.
developed to assess medication-taking in outpatients treated for high blood pressure.
Purpose: To provide a brief screening measurement of adherence with treatment.
Useful Facts: The Morisky Scale has four items with dichotomous (yes/no) response
options. The sum of 'yes' responses provides a total score of nonadherence. The Scale has been used extensively
among patients with varying medical conditions. It has been noted that some researchers question the item "Do you
ever forget to take your medicine?" because it might not distinguish between those who regularly forget their
doses and those who have forgotten a few times only.
VA Relevance: No information has been found regarding the use of this instrument
with veteran populations.
Availability:
References:
- Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication
adherence.Med Care. 1986 Jan;24(1):67-74.
[Abstract ]
- Gao X, Nau DP. Congruence of three self-report measures of medication adherence among HIV patients. Ann
Pharmacother 2000;34:1117-22.
[Abstract ]
- Shalansky SJ, Levy AR, Ignaszewski AP. Self-reported Morisky score for identifying nonadherence with
cardiovascular medications. Ann Pharmacother. 2004 Sep;38(9):1363-8. Epub 2004 Jul 6.
[Abstract ]
2. Adult AIDS Clinical Trials Group (AACTG) Adherence Instruments
Development: The AACTG Adherence Instruments include two self-report instruments
originally designed for use in the AACTG to assess adherence for treatment and its correlates. They were initially
administered to 75 HIV/AIDS patients taking combination antiretroviral therapy at ten different sites across the U.S.
Purpose: To assess compliance with combination antiretroviral therapy (ART).
Useful Facts: Administration time is approximately 10 minutes for each instrument.
The instruments focus on recent adherence (as early as 'yesterday'). One instrument specifically assesses adherence
to antiretroviral medications, while the other assesses the baseline correlates of adherence. The baseline correlates
questionnaire is completed only upon entry into the trial or study. The questionnaires have been translated into
French, Italian, and Spanish. The current baseline and adherence questionnaires include an additional section
developed by Drs. Linda Rabaneck and Amy Justice. The instruments are available at the Center for AIDS Prevention Studies.
VA Relevance: No information has been found regarding the use of these instrument
with veteran populations.
Availability: The instruments are available at the Center for AIDS Prevention
Studies website http://www.caps.ucsf.edu/tools/surveys/
References:
- Center for AIDS Prevention Studies Instruments. Center for AIDS Prevention Studies. Accessed July 2005.
Available URL: http://www.caps.ucsf.edu/projects/instrumentindex.html#8.
- Chesney MA, Ickovics JR, Chambers DB, Gifford AL, Neidig J, Zwickl B, Wu AW. Self-reported adherence to
antiretroviral medications among participants in HIV clinical trials: the AACTG adherence instruments. Patient
Care Committee & Adherence Working Group of the Outcomes Committee of the Adult AIDS Clinical Trials Group
(AACTG). AIDS Care. 2000 Jun;12(3):255-66.
[Abstract ]
- Reynolds NR, Testa MA, Marc LG, Chesney MA, Neidig JL, Smith SR, Vella S, Robbins GK; Protocol Teams of ACTG
384, ACTG 731 and A5031s. Factors influencing medication adherence beliefs and self-efficacy in persons naive
to antiretroviral therapy: a multicenter, cross-sectional study.AIDS Behav. 2004 Jun;8(2):141-50.
[Abstract ]
3. General Adherence Scale (GAS)
Development: The General Adherence Scale items were first published as part of the
Medical Outcomes Study (MOS) to assess the treatment adherence of patients with diabetes, hypertension, and heart
disease. Data were collected on patients from three systems of care (health maintenance organizations/HMOs, large
multispecialty groups/LMSGs, and private practices in Boston, Chicago, and Los Angeles. The items assess a
patient's self-reported success with adhering to recommendations as well as the ease of following such recommendations.
Purpose: To assess patients' general tendency to adhere to a prescribed medical
treatment. It provides an overall look at patient difficulty and success with following recommendations.
Useful Facts: The GAS takes less than 5 minutes to administer. There are five items
that are scored on a 6-point Likert scale from 'none of the time' (1) to 'all of the time' (6). Responses are
averaged after reversing the scoring of items 1 and 3, and transformed to a linear 0 - 100 distribution. (Ref:
1) A higher score means a higher degree of adherence to medical recommendations.
VA Relevance: No information has been found regarding the use of these instrument
with veteran populations.
Availability: The instrument is available from the RAND website.
http://www.rand.org/health/surveys_tools/mos/mos_adherence.html
References:
- DiMatteo MR, Hays RD, Sherbourne CD. Adherence to cancer regimens: implications for treating the older patient.
Oncology.1992 Feb;6(2 Suppl):50-7.
[Abstract ]
- DiMatteo MR, Sherbourne CD, Hays RD, Ordway L, Kravitz RL, McGlynn EA, Kaplan S, Rogers WH. Physicians'
characteristics influence patients' adherence to medical treatment: results from the Medical Outcomes Study.
[Abstract ]
- Hays RD. The medical outcomes study (MOS) measures of patient adherence. [serial online]. Accessed July 2005.
Available URL: http://www.rand.org/health/surveys_tools/mos/mos_adherence.html.
[created 1 Aug 2005]
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