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Health Services Research & Development

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National Mentoring Network (MNET) Mentor Profiles

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Alesha B. Castillo, PhD
Alesha B. Castillo, PhD
New York University

Research Interests: mechanical regulation of stem cell activation, recruitment, and lineage commitment

Alesha B Castillo, PhD, is an Assistant Professor in the Departments of Mechanical Engineering and Orthopaedic Surgery at New York University. Dr. Castillo’s research focuses on interactions between mechanobiological cues and musculoskeletal homeostasis, regeneration, and aging, with consideration given at the molecular, cellular and tissue levels. Specific areas of interest include mechanical regulation of stem cell activation, recruitment, and lineage commitment. Interdisciplinary work in her lab is grounded in engineering fundamentals, cell and molecular biology, and translational medicine with the goal of developing novel treatment strategies for age- and disease-related bone loss, disuse osteopenia, volumetric tissue deficits, and fracture repair. Her work is funded by the Department of Veterans Affairs, the AO Foundation, the NYU Center for Skeletal and Craniofacial Biology, and the NYU Clinical and Translational Science Institute. Dr. Castillo has been involved in peer-review activities for the VA Office of Research and Development and the NIH CSR Skeletal Biology Structure and Regeneration Study Section, and she currently serves as an Associate Editor for Clinical Reviews in Bone and Mineral Metabolism.

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