The SPTD is a publicly available database of study-level data from published suicide prevention trials in adults.
Randomized controlled trials (RCT)
Non-randomized controlled trials (Non-RCT)
Publications
About SPTD
The SPTD is a publicly available database of study-level data from published trials of suicide prevention approaches in adults. The database may be used for future systematic reviews or clinical practice guidelines, for identifying research gaps, and as an information resource for clinicians, patients, policymakers, and family members. Similar to other clinical trial databases such as the PTSD-Repository, the SPTD utilizes systematic review methods to search for, identify, and compile data from relevant trials. Researchers abstract detailed data elements related to participant, intervention, comparator, outcome, and other study characteristics, and conduct risk of bias assessments. The search is updated approximately twice yearly to maintain an up-to-date database from 1980 forward. Data are available as Excel spreadsheets. Two Excel spreadsheets comprise the SPTD: one contains all RCTs and the other is all non-RCTs.
Recommended Citations
Denneson, L. M., O’Neil, M. E., Veazie, S., Hannon, S., Baker-Robinson, W., Krushnic, D., Clauss, K., Carlson, K., Hamblen, J., & Constans, J. (2025). SPTD: Suicide Prevention Trials Database. sptd.cfm
O'Neil ME, Veazie S, Krushnic D, et al. Introducing the suicide prevention trials database: A publicly available data repository of suicide prevention studies. Suicide Life Threat Behav. 2025;55(1):e13152. doi:10.1111/sltb.13152 https://pmc.ncbi.nlm.nih.gov/articles/PMC11791465/
Funder
This project is jointly funded by a service directed research award to Dr. Denneson and Dr. O’Neil from VA Clinical Science Research and Development (CSR&D) (Award # SDR-SPTD-20S); a Quality Enhancement Research Initiative (QUERI) Partnered Evaluation Initiative award to Dr. O’Neil and Dr. Denneson (1I50HX004126); and VA Office of Suicide Prevention Demonstration Project funding to Drs. Denneson and O’Neil.
Partners
The Office of Suicide Prevention serves as a VA operational partner and the Suicide Prevention Research Impact NeTwork (SPRINT) serves as a project partner.
SPTD Co-Principal Investigators:
SPTD Team:
SPTD VA Operational Partners:
Archive of Prior SPTD Documents and Updates
Questions?
Email lauren.denneson@va.gov or maya.oneil@va.gov with any questions.
Learn more about the Office of Research and Development’s portfolio of suicide prevention research at Suicide Prevention Research (va.gov)