Suicide Prevention Trials Database (SPTD)

The SPTD is a publicly available database of study-level data from published suicide prevention trials in adults.

Randomized controlled trials (RCT)

• Access the Current SPTD RCT Excel Database (Updated April 2026; includes studies published January 1, 1980 through November 4, 2025)
• Data Dictionary in Word or Excel for RCTs in SPTD (Updated April 2026)
• Interactive SPTD RCT Data Dashboard
• What Interventions Have Been Studied (SPTD RCT Data Summary Updated June 2025)
• Who Has Been Studied (SPTD RCT Data Summary Updated June 2025)

Non-randomized controlled trials (Non-RCT)

• Access the Current SPTD Non-RCT Excel Database (Updated June 2025; includes studies published January 1, 1980 through Nov 6, 2024)
• Data Dictionary Excel file for Non-RCTs in SPTD (Updated June 2025)

Publications

• Introducing the Suicide Prevention Trials Database

About SPTD

The SPTD is a publicly available database of study-level data from published trials of suicide prevention approaches in adults. The database may be used for future systematic reviews or clinical practice guidelines, for identifying research gaps, and as an information resource for clinicians, patients, policymakers, and family members. Similar to other clinical trial databases such as the PTSD-Repository, the SPTD utilizes systematic review methods to search for, identify, and compile data from relevant trials. Researchers abstract detailed data elements related to participant, intervention, comparator, outcome, and other study characteristics, and conduct risk of bias assessments. The search is updated approximately twice yearly to maintain an up-to-date database from 1980 forward. Data are available as Excel spreadsheets. Two Excel spreadsheets comprise the SPTD: one contains all RCTs and the other is all non-RCTs.

How to Cite the SPTD

Denneson, L. M., O’Neil, M. E., Veazie, S., Hannon, S., Baker-Robinson, W., Krushnic, D., Clauss, K., Carlson, K., Hamblen, J., & Constans, J. (2025). SPTD: Suicide Prevention Trials Database. sptd.cfm

O'Neil ME, Veazie S, Krushnic D, et al. Introducing the suicide prevention trials database: A publicly available data repository of suicide prevention studies. Suicide Life Threat Behav. 2025;55(1):e13152. doi:10.1111/sltb.13152 https://pmc.ncbi.nlm.nih.gov/articles/PMC11791465/

Funder

This project is jointly funded by a service directed research award to Dr. Denneson and Dr. O’Neil from VA Clinical Science Research and Development (CSR&D) (Award # SDR-SPTD-20S); a Quality Enhancement Research Initiative (QUERI) Partnered Evaluation Initiative award to Dr. O’Neil and Dr. Denneson (1I50HX004126); and VA Office of Suicide Prevention Demonstration Project funding to Drs. Denneson and O’Neil.

Partners

The Office of Suicide Prevention serves as a VA operational partner and the Suicide Prevention Research Impact NeTwork (SPRINT) serves as a project partner.

SPTD Principal Investigator

• Maya O’Neil, PhD
• Previous Principal Investigator: Lauren Denneson, PhD

SPTD Team:

Joren Adams, PhD  Azrah Ahmed, MPH Chandler Atchison, MS William Baker-Robinson, MS Christina Bougatsos, MPH Kathleen Carlson, PhD Tamara Cheney, MD Kate Clauss, PhD Tracy Dana, MLS Jessica Hamblen, PhD

Sara Hannon, MS Danielle Krushnic, MPH Mandy Lewis, MS Bryce O’Shea, BA Miranda Pappas, MA Emily Sano, MA Stephanie Veazie, MPH Mesa Willis, MPH Emily Young, BS

SPTD VA Operational Partners:

• Mark Reger, PhD, Suicide Prevention - Actively Managed Portfolio, Office of Research & Development
• Susan Strickland, PhD, LCSW, Office of Suicide Prevention

Archive of Prior SPTD Files

If you would like to access an archived file, please contact us.

Questions?

Email maya.oneil@va.gov or sara.hannon@va.gov with any questions.

Learn more about the Office of Research and Development’s portfolio of suicide prevention research at Suicide Prevention Research (va.gov)

Questions about the HSR website? Email the Web Team

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.