1051. Identifying Minority Recruitment Strategies for SELECT
Michael S Wolf, PhD, MPH
Objectives: This study examined barriers to recruitment in the Selenium and Vitamin E Cancer Prevention Trial (SELECT) among African American and Latino Veterans.
Methods: We conducted 8 focus groups with 46 Veterans in Chicago, Illinois and Phoenix, Arizona. Discussions were audiotaped and transcribed for content analysis. Emergent themes were compared with existing literature to develop low literacy, culturally targeted SELECT recruitment videos and brochures. Four major themes emerged from the discussions: 1) knowledge of prostate cancer, 2) knowledge of clinical trials, 3) trust in the healthcare system, and 4) strategies to improve clinical trials participation.
Results: Overall, participants lacked knowledge of the location and function of the prostate but were acutely aware of the threat of prostate cancer, their risk for acquiring the disease, and wanted more information. Participants were less informed about clinical trials. Specifically, potential side effects, time commitment, consent forms, and confusion regarding the rationale of a placebo deterred participants. African Americans were suspicious of medical research, reiterating the distrust held by the community at large. As Veterans, many commented that military experience included the role of ‘guinea pig’.
Conclusions: Our findings suggest minority recruitment for cancer prevention trials such as SELECT should 1) make participation easy and understandable, 2) highlight the voluntary nature of participation, 3) be direct when communicating risks and benefits, and 4) target altruistic motives. Recruitment materials have been developed from these findings and are now being evaluated in a controlled clinical trial.