Evidence Synthesis Program (ESP) Center
Minneapolis VA Health Care System
Timothy J. Wilt, MD, MPH, Director
Wei Duan-Porter, MD, PhD, Associate Director
Greer N, Bart B, Billington C, Diem SJ, Ensrud KE, Kaka A, Klein M, Melzer A, Reule S, Shaukat A, Sheets K, Starks J, Vardeny O, McKenzie L, Duan-Porter W, Wilt, TJ. COVID-19 Post-acute Care Major Organ Damage: A Living Rapid Review. Evidence Synthesis Program, Health Services Research and Development Service, Office of Research and Development, Department of Veterans Affairs. VA ESP Project #09-009; 2020.
The purpose of this living rapid review is to determine the prevalence of post-acute care major organ damage and healthcare or service use needs associated with major organ damage in adults who were hospitalized with or for COVID-19. The topic was nominated by the VA Evidence Synthesis Program Coordinating Center in collaboration with VHA clinical and operations partners in order to guide future clinical care decisions and resource needs related to COVID-19. It is 1 in a series of 3 living rapid reviews conducted across VA ESP sites addressing post-acute care prevalence related to: 1) mental health, 2) rehabilitation/functional status, and 3) major organ damage in patients hospitalized with or for COVID-19.
1. What is the post- acute care prevalence of major organ damage among adults hospitalized with or for proven COVID-19 disease?
2. Does the post-acute care prevalence of major organ damage among adults with or for COVID-19 disease vary by patient characteristics (eg, age, sex, race/ethnicity, preexisting co-morbidities/frailty, place of residence), COVID-19 disease severity, or other factors (eg, treatment for COVID-19)?
3. What are the short- (< 3 months) and long-term (>3> 3 months) healthcare or service use needs of adults surviving COVID-19 disease with major organ damage?