VA HSR&D Research Topics: Depression
Depression (major depressive disorder or clinical depression) is a common but serious mood disorder. It causes severe symptoms that affect feelings, thoughts, and the ability to handle daily life activities. It’s estimated that 18.5% of service members returning from Iraq or Afghanistan have either post-traumatic stress disorder (PTSD) or depression. VA conducts a wide variety of research that looks at depression treatment, prevention, and access to mental health services.
Search results were generated based on the search term "Depression". Results are updated weekly, as new data are available.
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(5 of more than 1568 DEPRESSION focused publications)
- Wang L, Kroenke K, Stump TE, Monahan PO. Screening for perinatal depression with the Patient Health Questionnaire depression scale (PHQ-9): A systematic review and meta-analysis. General hospital psychiatry. 2020 Dec 21; 68:74-82.
- Vest BM, Wray LO, Brady LA, Thase ME, Beehler GP, Chapman SR, Hull LE, Oslin DW. Primary care and mental health providers' perceptions of implementation of pharmacogenetics testing for depression prescribing. BMC psychiatry. 2020 Oct 28; 20(1):518.
- Mavandadi S, Ingram E, Chen S, Klaus J, Oslin D. The association between social ties and changes in depressive symptoms among veterans enrolled in a collaborative depression care management program. Psychological Services. 2020 Oct 8.
- McClendon J, Essien UR, Youk A, Ibrahim SA, Vina E, Kwoh CK, Hausmann LRM. Cumulative Disadvantage and Disparities in Depression and Pain among Veterans with Osteoarthritis: The Role of Perceived Discrimination. Arthritis care & research. 2020 Oct 7.
- Desilet LW, England BR, Michaud K, Barton JL, Mikuls TR, Baker JF. Posttraumatic Stress Disorder, Depression, Anxiety, and Persistence of Methotrexate and TNF Inhibitors in Patients with Rheumatoid Arthritis. ACR open rheumatology. 2020 Oct 1; 2(10):555-564.
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(5 of more than 154 DEPRESSION focused publication briefs)
- VA Mental Health Use During Pregnancy/Postpartum Periods Remained Strong among Women with Prepregnancy Depression, PTSD, and Anxiety Diagnoses
This study examined how prepregnancy psychiatric diagnoses could impact mental health treatment use during pregnancy and postpartum, given there is increased risk of symptom recurrence and/or medication discontinuation during pregnancy. Findings showed that there was a strong correlation between a prepregnancy diagnosis of major depressive disorder (MDD), PTSD, or anxiety and use of mental healthc...
Date: November 18, 2020
- VA’s Primary Care-Mental Health Integration Affects Access Differently for Women and Men Veterans
This study of 5.4 million Veterans (including 448,455 women), who received care at one of 396 VA primary care clinics between FY2013 and FY2016, set out to answer the following question: Did VA’s national Primary Care-Mental Health Integration (PC-MHI) initiative improve access to care equally among men and women Veterans? Findings showed that PC-MHI was associated with greater use of all outpatie...
Date: October 20, 2020
- Both PTSD Symptoms and Moral Injury are Associated with Adverse Perinatal Outcomes among Women Veterans
This longitudinal study is the first to examine the impact of PTSD symptoms and moral injury on adverse perinatal outcomes among women who became pregnant in the first three years after separating from military service. Findings showed that after adjusting for age, racial/ethnic minority status, socioeconomic status, and lifetime trauma, both PTSD symptoms and moral injury were associated with adv...
Date: June 1, 2020
- Positive IPV Screen Significantly Associated with Health Outcomes and Healthcare Use among Women Veterans Over 45
This study examined the proportion of women older than childbearing age who screen positive when routinely screened for past-year intimate partner violence (IPV) at VA clinics, as well as associations of a positive screen with health conditions and use of healthcare services. Findings showed that of the study cohort, 255 middle-aged (45-59 years; 9%) and 79 older (60 years and older, 5%) women scr...
Date: April 21, 2020
- Computer-Based Cognitive Behavioral Therapy with Peer Support Provides Greater Improvement of Depression Symptoms
This trial sought to determine whether computer-based cognitive behavioral therapy (cCBT) combined with peer support improved outcomes relative to enhanced usual care (EUC) for 330 primary care patients with depression who were treated at three Midwestern VA medical centers and two of their associated outpatient clinics. Findings showed that peer-supported cCBT as an add-on to usual primary care t...
Date: March 1, 2020
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( 5 of more than 103 DEPRESSION focused projects
|| Changes in the Delivery of Evidenced Based Psychotherapies for Depression and PTSD as the Result of COVID-19 Pandemic
|| Improving Depression Management in Primary Care
|| Does Choice Equal Quality? A Mixed-Methods Comprehensive Evaluation of the Quality of Community Care through the MISSION Act vs VA care for Veterans with PTSD, Depression and Chronic Pain
|| Implementing the Behavioral Activities Intervention (BE-ACTIV) to Reduce Depression among Veterans in Community Living Centers
|| HIV Translating Initiatives for Depression into Effective Solutions – Hyb
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