Health Services Research & Development

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Methicillin-resistant Staphylococcus aureus (MRSA)

Methicillin-resistant Staphylococcus aureus (MRSA) is a type of bacteria that is resistant to certain antibiotics called beta-lactams. MRSA is a dangerous infection that can cause pneumonia or infect wounds and the bloodstream. It is primarily spread through direct physical contact with a person or object carrying the bacteria, and typically resides on the skin or in the nose. Both healthcare settings (hospitals, clinics, nursing homes) and healthcare procedures play a role in MRSA transmission, and VA research focuses on preventing MRSA transmission through a variety of approaches.

Search results were generated based on the search term "MRSA". Results are updated weekly, as new data are available.

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(5 of more than 55 MRSA focused publications)

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Publication Briefs

(5 of more than 6 MRSA focused publication briefs)

  • MRSA Prevention Initiative Results in Additional Significant Decline in Other Bacteremia Rates across 130 VHA Facilities
    VA introduced the Methicillin-resistant Staphylococcus aureus (MRSA) Prevention Initiative in 2007. Although the Initiative was perceived as only targeting MRSA, it also expanded infection prevention and control programs and resources, which could result in lower rates of infection with other pathogenic bacteria. This study assessed the effect of the MRSA Initiative on hospital-onset gram-negative...
    Date: June 28, 2016
  • Targeted Cost-Saving Method for MRSA and VRE Surveillance in VA Hospitals
    Emerging antibiotic-resistant bacteria, including MRSA (methicillin-resistant Staphylococcus aureus) and VRE (vancomycin-resistant enterococcus), are leading causes of infections in hospitalized patients that result in significant costs, morbidity, and mortality. This prospective study investigated alternative methods for targeted active surveillance (using a prediction rule to identify a group of...
    Date: December 1, 2010
  • Responding to Decline in MRSA Infection
    This JAMA Editorial reports on the current status of MRSA (methicillin-resistant S aureus) infection rates – and what it may mean for the future. Using data from 2005-2008, the CDC’s surveillance system showed a continuous decline of invasive MRSA disease. This includes an estimated 9.4% annual decrease in hospital onset and an estimated 5.7% annual decrease in healthcare-associated community-onse...
    Date: August 11, 2010
  • Implementation of a VA Quality Improvement Initiative Improves Knowledge and Perceptions Regarding MRSA Prevention
    Implementation of the initiative at 17 VAMCs was associated with temporal improvements in knowledge and perceptions regarding MRSA prevention. Between baseline and follow-up, there were increases in the number of respondents who: correctly identified that alcohol-based hand rub is more effective at inactivating MRSA than soap and water, reported cleaning their hands when entering and exiting a pa...
    Date: February 3, 2010
  • Toyota Production System Methodology Leads to Improved Peri-Operative Care in One VAMC
    In the Toyota Production System (TPS) industrial engineering approach, front-line work groups identify problems, experiment with possible solutions, measure the results, and implement strategies to improve quality, resulting in a “ground-up” rather than “top-down” approach to solving system problems. Beginning in 2001, one VAMC instituted TPS methods to reduce Methicillin Resistant Staphylococcus ...
    Date: September 1, 2009

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( 5 of more than 24 MRSA focused projects )

Project No.  Title  PI  Funding Start   
CRE 12-286 Preventing MRSA infections: a virtual comparative effectiveness model Rubin, Michael 2015-04-01
CRE 12-291 Checklist to Prevent MRSA Surgical Site Infections Perencevich, Eli 2014-04-01
CDA 11-210 Using Economics and Epidemiology to Evaluate MRSA Decolonization in the VA Nelson, Richard 2013-03-01
CDP 13-003 Using Economics and Epidemiology to Evaluate MRSA Decolonization in the VA (CDA 11-210) Nelson, Richard 2013-03-01
RRP 09-163 Assessment of MRSA prevention practice in VA Spinal Cord Injury Centers Evans, Charlesnika 2010-04-01

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HSR&D Briefs, Reports, Newsletters

5 sample "MRSA" publications displayed.

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Topic Spotlight

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The most recent "MRSA" seminars are displayed.

Date Title Presenter(s)
6/14/2016 Economic Evaluation of Interventions to Prevent Healthcare-Associated Infections in the VA Nelson, Richard  
7/16/2014 Estimating the cost of healthcare-associated MRSA infections in the VA Nelson, Richard  

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Other Resources

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