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Spotlight on Evidence Synthesis Program

Benefits and Harms of Treating Blood Pressure in Older Adults: A Systematic Review and Meta-analysis


by Dawn Bravata, MD ; William Cushman, MD ; Glenn Graham, MD, PhD ; Devan Kansagara, MD, MCR ; Jessica Weiss, MD, MCR
Seminar date: 10/5/2016

Description: Operational Partner discussants: Glenn Graham, MD, Deputy National Director of Neurology, Department of Veterans Affairs Dawn Bravata, MD, Core Investigator, VA HSR&D Center for Health Information and Communication, Indianapolis VA Medical Center William Cushman, MD, Chief of Preventive Medicine Section, Memphis VA Medical Center Hypertension is a very common chronic illness in the United States and among Veterans. Use of antihypertensive medications can lower the risk of cardiovascular disease, cerebrovascular disease, renal disease, and death. The most beneficial blood pressure targets for patients of specific age groups, however, has been a topic of some debate and controversy, stemming from concerns that the ratio of benefit to harm of a given blood pressure level may vary with age. The objectives of this review are to examine the benefits and harms of differing blood pressure targets among adults over age 60. Intended audience: Researchers, clinicians, and others interested in blood pressure treatment in older adults.



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