Hypertension, or high blood pressure, is a long-term, chronic condition in which the force exerted by the blood against the walls of the blood vessels exceeds a commonly accepted safe range. Hypertension, if left untreated, can lead to severe complications including an increased risk for heart attack and stroke. Within VA, research into hypertension can include medication safety, non-pharmacologic interventions, care delivery, and care access for Veterans.
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(5 of more than 51 HYPERTENSION focused publication briefs)
- Common Drugs for Hypertension and Diabetes Not Associated with Severe COVID-19 Illness or Testing Positive for COVID-19
Originally requested by the World Health Organization (WHO), this systematic review examined the relationship between angiotensin-converting enzyme inhibitors (ACEI) or angiotensin-receptor blockers (ARB) use and COVID-19 illness. Findings showed that high-certainty evidence suggests that ACEI or ARB use is not associated with more severe COVID-19 illness, and moderate-certainty evidence suggests ...
Date: May 15, 2020
- Six Readily Available Processes of Care Can Decrease Mortality for Individuals with TIA or Non-Severe Stroke
This study sought to identify specific processes of care that are associated with reduced risk of recurrent stroke or death among patients with TIA or non-severe stroke. Six processes were found to be effective in acute TIA management studies: brain imaging, carotid artery imaging, hypertension medication intensification, high-moderate potency statin, antithrombotics, and anticoagulation for atria...
Date: July 3, 2019
- Underuse of Statins among Veterans with Hypercholesterolemia
This study sought to examine the prevalence and treatment of Veterans with uncontrolled severe hypercholesterolemia who received VA healthcare. Findings showed a marked underuse of statins in Veterans with uncontrolled severe hypercholesterolemia. Within six months of this abnormal lab value, only 52% were being treated with statins, and less than 10% were on high-intensity statin therapy as recom...
Date: September 1, 2018
- Impact of Intensive BP Therapy on Patient-Reported Outcomes
This randomized controlled trial compared two strategies for managing systolic blood pressure (SBP) in older adults with hypertension – an intensive strategy with an SBP target of <120 mmHg versus a standard care strategy targeting <140 mmHg – and whether such intensive therapy affects patient-reported outcomes. Findings showed that intensive therapy resulted in a 14.8 mmHg lower blood pressure co...
Date: August 24, 2017
- PACT Initiative Did Not Reduce Most Disparities in Improved Hypertension or Diabetes Control among VA Patients
This study sought to determine whether PACTs helped mitigate national racial/ethnic disparities in VA clinical outcomes, after adjusting for variable implementation and social determinants of health. Findings showed that improvements in clinical outcomes for hypertension and diabetes control had not been achieved for whites or most racial/ethnic groups four years into VA’s system-wide roll-out of ...
Date: June 1, 2017
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