Cancer Care and Prevention
Cancer occurs when some of the body’s cells divide without stopping and spread into surrounding tissues. Malfunctioning genes trigger the formation of cancer cells, and those malfunctions may be inherited, or may arise as a result of damage to DNA caused by certain environmental exposures—including chemicals or ultraviolet radiation. Cancer screenings are a key preventive care measure, and can help detect cancer in its early stages—which can contribute to early treatment, increased survival rates, and better health outcomes.
VA conducts cancer research to help better understand how Veterans’ military experience may impact the development of certain cancers; how lifestyle choices known to cause cancer—such as tobacco use—may disproportionately impact them; and to build the evidence-base for effective, appropriate cancer screening tests and tools.
Each "widget" below is populated by a dynamic search of the HSR&D website and its underlying databases. Search results are generated based on the search term "Cancer". Results are updated regularly, as new data are available.
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(5 of more than 3455 CANCER focused publications)
- Marcotte LM, Deeds S, Wheat C, Gunnink E, Gray K, Rojas J, Finch C, Nelson K, Reddy A. Automated Opt-Out vs Opt-In Patient Outreach Strategies for Breast Cancer Screening: A Randomized Clinical Trial. JAMA internal medicine. 2023 Sep 11.
- Huston-Paterson H, Mao Y, Tseng CH, Kim J, Yeh MW, Wu JX. Disparities in Initial Thyroid Cancer Care by Hospital Treatment Volume: Analysis of 52,599 Cases in California. Thyroid : official journal of the American Thyroid Association. 2023 Sep 4.
- O'Hanlon CE, Walling AM, McClean M, Chu K, Lindvall C, Lee M, Stockdale SE, Leung LB. Depression care quality among patients with solid tumor cancers detected to have depression in Veterans Health Administration primary care clinics. Psychological Services. 2023 Aug 24.
- Anyane-Yeboa A, Aubertine M, Parker A, Sylvester K, Levell C, Bell E, Emmons KM, May FP. Use of a mixed-methods approach to develop a guidebook with messaging to encourage colorectal cancer screening among Black individuals 45 and older. Cancer medicine. 2023 Aug 21.
- Ahmed A, Hippe DS, Snidarich M, Crothers K, Triplette M. Delays in Recommended Follow-Up after Positive Findings in Lung Cancer Screening. Annals of the American Thoracic Society. 2023 Aug 1; 20(8):1175-1181.
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(5 of more than 94 CANCER focused publication briefs)
- Colorectal Cancer Screening Uncommon in Veterans Aged 76-85, Varying Only Slightly by Predicted Life Expectancy
Previous research suggests few adults aged >75 receive colorectal cancer (CRC) screening, raising concerns that healthy individuals aged >75 years old who may benefit from continued screening are not being screened. Findings from this study showed that among Veterans aged 76-85 years, CRC screening was uncommon and varied only slightly by predicted life expectancy. Overall, the cumulative incidenc...
Date: September 7, 2023
- Weight-Based Dosing with Pharmacy-Led Stewardship Could Reduce Cancer Drug Spending by Millions
This simulation analysis assessed the extent to which combining personalized weight-based dosing with common stewardship efforts at the pharmacy level that are supported by clinical pharmacy evidence (i.e., dose rounding and vial sharing) would reduce use of a common class of cancer therapies, immune checkpoint inhibitors (ICIs), thus, lowering spending. Findings showed that VA could save upward o...
Date: July 5, 2023
- Quality of Treatment for Veterans with Early-Stage Lung Cancer Varies Widely and is Associated with Survival
Most lung cancer treatment guidelines recommend several surgical quality metrics (QMs) that should be met for all patients diagnosed with early-stage non-small cell lung cancer (NSCLC). VA Lung Cancer Operative quality (VALCAN-O) comprises 5 quality measures. This study sought to determine the association between adherence to these metrics and overall survival and recurrence-free survival among Ve...
Date: March 1, 2023
- Factors Associated with Refusal of Lung Cancer Screening When Offered by VA Physicians
This study sought to determine how frequently patients decline lung cancer screening (LCS) when it is offered by a physician – and to define patient and facility-level factors associated with their decision. Findings showed that in this study cohort of more than 43,200 Veterans, approximately one-third declined lung cancer screening following a discussion with their physician. The physician and fa...
Date: August 16, 2022
- Excess Mortality Rates among Post-9/11 Veterans Compared with General US Population, Particularly among Veterans with TBI
This study sought to assess the total all-cause and cause-specific mortality burden – and to estimate the total number of excess deaths among post-9/11 Veterans with and without exposure to traumatic brain injury (TBI) compared with the total US population. Findings showed that post-9/11 Veterans experienced excess all-cause and cause-specific mortality compared with the total US population, which...
Date: February 11, 2022
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( 5 of more than 91 CANCER focused projects
|| Optimizing Advanced Prostate Cancer Care Among US Veterans
|| Developing and Pilot-testing a Yoga Program to Address Post-prostatectomy Side-effects Among Veterans with Prostate Cancer
|| Patient Risk Perception and Decision-Making about Adherence to Repeat Cancer Screening
|| Identifying Risk Factors for New Persistent Opioid Use Among Veterans Following Treatment for Early Stage Cancer
|| Defining Quality of Care in Lung Cancer
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HSR&D Briefs, Reports, Newsletters
5 sample "Cancer" publications displayed.
Non-surgical Therapies for Early-stage Non-small Cell Lung Cancer: A Systematic Review
...for Early-stage Non-small Cell Lung Cancer: A Systematic Review...for Early-stage Non-small Cell Lung Cancer: A Systematic Review Evidence Synthesis...for Early- stage Non-small Cell Lung Cancer Recommended citation: Sultan S, Ullman
Process Access Data
...significantly less likely to receive colon cancer screening than TRICARE retired whites...database. Cancer Epidemiol Biomarkers Prev. 2009;18(4):1208-1212. 1532 Cancer (prostate)
Improving Cancer Care || In Progress
...Cancer is soon expected to be the leading cause of death in the United States...million people are diagnosed with cancer and more than 500,000 people die of...Improving Cancer Care Overview Individual Research Studies on Cancer Multilevel...Hepatocellular Cancer Helping Optimize Information for Cancer and Effective Pain
Overview: Improving Cancer Care || In Progress
...Cancer is soon expected to be the leading cause of death in the United States...million people are diagnosed with cancer and more than 500,000 people die of...Improving Cancer Care » Table of Contents Improving Cancer Care Overview Cancer is...million people are diagnosed with cancer and more than 500,000 people die of
Incorporating Veterans' Preferences into Lung Cancer Screening Decisions || In Progress
...Cancer is soon expected to be the leading cause of death in the United States...million people are diagnosed with cancer and more than 500,000 people die of...February 2018 In this Issue: Improving Cancer Care » Table of Contents Incorporating...Incorporating Veterans’ Preferences into Lung Cancer Screening Decisions Feature Article
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