Health Services Research & Development

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Research Topics

Substance Use Disorder: Opioids

Substance use disorders (SUD), including the abuse of alcohol, prescription medications, or opioids, can lead to significant negative consequences to an individual's mental and physical health, work performance, housing status, and social functioning. Important issues being studied include alcohol screening and brief counseling, SUD specialty care, and the treatment of common comorbidities (i.e., SUD and PTSD or SUD and chronic pain).

Search results were generated based on the search term "Opioid". Results are updated weekly, as new data are available.

VIEW: Citations | Publication Briefs | Studies | HSR&D Briefs, Reports, Newsletters | Cyberseminars | Videos | Podcasts | Other Resources


(5 of more than 515 OPIOID focused publications)

  • Hawkins EJ. Opioid and Benzodiazepine Co-prescribing and Mortality among VA Patients with Posttraumatic Stress Disorder. HSR&D CyberSeminars [Cyberseminar]. HSR&D. 2018 Jun 11.
  • Minegishi T, Frakt A. Reducing Long-term Opioid Use in the Veterans Health Administration. Journal of general internal medicine. 2018 Jun 1; 33(6):781-782.
  • Spivak S, Cullen B, Eaton W, Nugent K, Spivak A, Fenton A, Rodriguez K, Mojtabai R. Prescription opioid use among individuals with serious mental illness. Psychiatry Research. 2018 May 31; 267:85-87.
  • Alzeer AH, Jones J, Bair MJ. Review of Factors, Methods, and Outcome Definition in Designing Opioid Abuse Predictive Models. Pain medicine (Malden, Mass.). 2018 May 1; 19(5):997-1009.
  • Carey EP, Nolan C, Kerns RD, Ho PM, Frank JW. Association Between Facility-Level Utilization of Non-pharmacologic Chronic Pain Treatment and Subsequent Initiation of Long-Term Opioid Therapy. Journal of general internal medicine. 2018 May 1; 33(Suppl 1):38-45.

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Publication Briefs

(5 of more than 37 OPIOID focused publication briefs)

  • Then and Now: Medications for Opioid Use Disorder in VA
    As the largest provider of substance use disorder treatment in the nation, VA has taken proactive steps to increase access to medications indicated for opioid use disorder (OUD), which is an essential component of evidence-based care. This article examines the history of those medications (methadone, buprenorphine, and injectable naltrexone) within VA, as well as early and ongoing efforts to incre...
    Date: March 29, 2018
  • State-based Prescription Drug Monitoring Programs Might Help Increase Opioid Prescribing Safety among Veterans Using VA and Non-VA Healthcare
    This study evaluated VA physicians’ perspectives and experiences regarding the use of state-based Prescription Drug Monitoring Programs (PDMPs) to monitor Veterans’ receipt of opioids from non-VA prescribers. Findings showed that VA primary care physicians broadly embraced PDMPs as a tool to monitor Veterans’ receipt of opioids from non-VA sources despite identifying multiple barriers to optimal u...
    Date: March 8, 2018
  • Opioids Do Not Result in Better Pain-Related Function or Pain Intensity Compared to Non-Opioid Drugs in Veterans with Chronic Pain
    This randomized trial compared opioid therapy versus non-opioid medication therapy over 12 months for primary care patients with chronic back pain or hip or knee osteoarthritis pain. Findings showed that the use of opioid therapy compared with non-opioid medication therapy did not result in significantly better pain-related function over 12 months. Opioid therapy compared with non-opioid medicatio...
    Date: March 6, 2018
  • Dual Use of VA and Medicare Associated with Substantial Increase in Risk of Potentially Unsafe Opioid Use among Veterans
    This study sought to estimate the prevalence and consequences of receiving prescription opioids from both VA and Medicare Part D for all dually-enrolled Veterans who filled a prescription opioid in either system in calendar year 2012. Findings showed that among Veterans dually enrolled in Medicare Part D and VA and receiving prescription opioids in 2012, more than 1 in 8 received opioids from both...
    Date: February 1, 2018
  • Declining Rates in VA Prescriptions for Long-Term Opioids
    This study sought to characterize the overall prevalence of opioid prescribing in the VA healthcare system from 2010 through 2016 by duration of use. Findings showed that opioid prescribing trends followed similar trajectories in VA and non-VA settings, peaking around 2012 and subsequently declining. The prevalence of VA opioid prescribing was 20.8% in 2010, 21.2% in 2012, and declined annually to...
    Date: January 29, 2018

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( 5 of more than 35 OPIOID focused projects )

Project No.  Title  PI  Funding Start   
IIR 17-039 Improving Veteran Health by Increasing Dental Stewardship of Antibiotics and Opioids Suda, Katie 2018-07-01
IIR 16-262 Association of Complementary and Integrative Health (CHI) Interventions with Opioid Use and Related Risks Among Veterans With Musculoskeletal Disorders (MSD) and PTSD Goulet, Joseph 2018-05-01
IIR 17-139 Cost Effectiveness of Interventions to Reduce Morbidity from Opioid Dependency Owens, Douglas 2018-04-01
IIR 16-145 Testing a Novel Strategy to Improve Implementation of Medication-Assisted Treatment for Veterans with Opioid Use Disorders in Low Performing Facilities Hagedorn, Hildi 2017-07-01
SDR 15-461 The Opioid Consent: Helping Optimize Information for Cancer and Effective (CHOICE) Pain Management Lorenz, Karl 2016-09-01

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HSR&D Briefs, Reports, Newsletters

5 sample "Opioid" publications displayed.

  • Managing Chronic Pain
    ...Managing Chronic Pain Emerging Evidence Managing Chronic Pain VA/HSR&D researchers conduct an extensive number of investigations designed to improve...

  • August 2012 FORUM FY10. Opioids are considered a core pain management tool, but long-term effectiveness of opioid therapy for chronic pain is untested, and opioid...

  • Assessment and Management of Acute Pain in Adult Medical Inpatients
    ...outcomes or safety? For inpatients with dependencies on tobacco, alcohol, stimulant, marijuana, or opioids, how do differences in assessment and...

  • FORUM PDF format. 11-2016: Care Management 08-2016: Provider to Payer: Transforming VA Care 05-2016: Chronic pain, opioids 11-2015: Access 08-2015:...

  • Pain in Patients with Polytrauma
    ...used to reduce pain in these individuals (for example, oral opioids) have the potential to interfere with the active rehabilitation needed to...

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The most recent "Opioid" seminars are displayed.

Date Title Presenter(s)
11/6/2018 Care Management for the Effective Use of Opioids (CAMEO): A Randomized Trial Bair, Matthew  
6/11/2018 Opioid and Benzodiazepine Co-prescribing and Mortality among VA Patients with Posttraumatic Stress Disorder Hawkins, Eric  
Malte, Carol  
6/4/2018 Data-Based Case Reviews of Patients with Opioid Related Risk Factors as a Tool to Prevent Overdose and Suicide Lewis, Eleanor  
2/6/2018 The VA Opioid Safety Initiative – how did we get here and what is ahead? Sandbrink, Friedhelm  
Moore, Von  
10/3/2017 Addressing Pain and Opioid Use Disorder in High Risk Patients Robeck, Ilene  

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Other Resources

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