Research Topics
Opioid Management
Opioids are a class of medication that are typically used to reduce and manage both acute- and long-term pain. Opioids can be both naturally occurring and synthetically manufactured, and encompass both legally and illegally made and used products. While they can be effective in reducing short-term acute pain, long-term use carries risks, including addiction and accidental overdose. In order to help effectively manage opioid prescribing and use, HSR researchers conduct investigations into various aspects of opioid management, including prescription medication reviews, adjunct pain management therapy, and opioid use disorder treatment.
Each section below is populated by a search of the HSR website. Search results are generated based on the search term "Opioid". Results are updated as new data are available.
VIEW: Citations | Publication Briefs | Studies | HSR Briefs, Reports, Newsletters | Cyberseminars | Videos | Podcasts | Other Resources
Citations
(5 of more than 1160 OPIOID focused publications)
- Takada S, Seamans MJ, Javanbakht M, Bone C, Ijadi-Maghsoodi R, Shoptaw S, Gelberg L. Nativity and the risk of opioid use disorder among Hispanic/Latinx women in primary care in Los Angeles, CA. Journal of ethnicity in substance abuse. 2024 Feb 7; 1-15.
- Acharya M, Hayes CJ, Li C, Painter JT, Dayer L, Martin BC. Opioid therapy trajectories of patients with chronic non-cancer pain over one year of follow-up after initiating short-acting opioid formulations. Pain medicine (Malden, Mass.). 2024 Jan 18; doi:10.1093/pm/pnad169.
- Dember LM, Hsu JY, Bernardo L, Cavanaugh KL, Charytan DM, Crowley ST, Cukor D, Doorenbos AZ, Edwards DA, Esserman D, Fischer MJ, Jhamb M, Joffe S, Johansen KL, Kalim S, Keefe FJ, Kimmel PL, Krebs EE, Kuzla N, Mehrotra R, Mishra P, Pellegrino B, Steel JL, Unruh ML, White DM, Yabes JG, Becker WC, HOPE Consortium. The design and baseline characteristics for the HOPE Consortium Trial to reduce pain and opioid use in hemodialysis. Contemporary clinical trials. 2023 Dec 10; 136:107409.
- Matthias MS, Myers LJ, Coffing JM, Carter JL, Daggy JK, Slaven JE, Bair MJ, Bravata DM, McGuire AB. Patterns of Opioid Prescriptions in the Veterans Health Administration for Patients With Chronic Low-Back Pain After the Onset of the COVID-19 Pandemic: A Retrospective Cohort Analysis. The journal of pain. 2023 Dec 9.
- Khouja T, Shah NH, Suda KJ, Polk DE. Trajectories of opioid prescribing by general dentists, specialists, and oral and maxillofacial surgeons in the United States, 2015-2019. Journal of the American Dental Association (1939). 2024 Jan 1; 155(1):7-16.e7.
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Publication Briefs
(5 of more than 72 OPIOID focused publication briefs)
- Giving Veterans an Active Voice in Creating a Veteran-Centered Chronic Pain Research Agenda
Veterans Action League (VAL) 2.0 was a two-year community engagement project (2019–2021) that sought to develop a national Veteran-centered chronic pain research agenda that includes Veteran-generated recommendations for chronic pain management and chronic pain research priorities. Findings showed that Veterans’ most frequently cited need for chronic pain management and treatment was better access...
Date: March 23, 2023
- VA Treatment of Opioid Use Disorder was Maintained During the COVID Pandemic Through Rapid Shift to Telehealth
At the beginning of the COVID pandemic, key federal policy changes were implemented to decrease barriers to telehealth-delivery of buprenorphine, a life-saving medication treatment for patients with opioid use disorder (OUD). This study examined the impact of these COVID-19 policies on buprenorphine treatment across different modalities (telephone, video, and in-person visits). Findings showed tha...
Date: July 28, 2022
- Antipsychotic Prescribing Decreased in VA Nursing Homes, but Prescribing Alternative Drugs, such as Opioids, Increased
This study sought to evaluate national trends in prescribing antipsychotic and other central nervous system (CNS)-active medications for Veterans with dementia residing in VA nursing homes, as well as how use has changed over time. Findings showed that antipsychotic use steadily decreased between FY2009 and FY2018 (from 34% to 28%), with similar declines in anxiolytic prescribing (from 34% to 27%)...
Date: May 26, 2022
- Predictive Tool Associated with 22% Lower Odds of All-Cause Mortality among High-Risk Veterans Taking Opioids
In 2018, VA mandated a case review intervention that targeted patients who had been prescribed opioid analgesics and who were at high risk of adverse outcomes. The Stratification Tool for Opioid Risk Mitigation (STORM), a provider-facing dashboard that uses predictive analytics to stratify patients prescribed opioids based on their risk for overdose/suicide, was developed to identify these patient...
Date: May 2, 2022
- High Virologic Cure Rates for Hepatitis C Virus among Veterans with Opioid Use Disorder Treated with Elbasvir/Grazoprevir
Elbasvir (EBR)/grazoprevir (GZR) is a fixed-dose combination treatment for hepatitis C virus (HCV). This study sought to evaluate the real-world effectiveness of EBR/GZR among Veterans with HCV genotype (GT) 1 who also had a diagnosis of opioid use disorder (OUD). Findings showed that high rates of virologic cure were achieved among VA patients with HCV, OUD, and multiple comorbidities, including ...
Date: January 25, 2022
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Studies
( 5 of more than 58 OPIOID focused projects
)
Project No. |
Title |
PI |
Funding Start |
IIR 22-062
|
Reducing Chronic Opioid Use Among Veterans Undergoing Community Care Surgery Using a Transitional Pain Service |
Brooke, Benjamin |
2024-02-01 |
IIR 20-122
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ECCO - Evaluation of Outcomes Associated with Community Care Prescribed Opioids |
Duan-Porter, Wei |
2023-03-01 |
SDR 21-108
|
Role of Non-pharmacological Pain Treatments in Safe and Effective Opioid Tapering in Chronic Pain |
Black, Anne |
2022-05-01 |
CDA 20-231
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Data to Clinical Action: Using Predictive Analytics to Improve Care of Veterans with Opioid Use Disorder |
Hayes, Corey |
2022-04-01 |
SDR 21-114
|
Virtual MOUD Treatment: Virtual Point-of-Care Toxicology Testing to Accompany Virtual Medication Assisted Treatment for Opioid Use Disorder |
Hermes, Eric |
2022-03-01 |
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Videos
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Podcasts
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