Health Services Research & Development

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Research Topics

Substance Use Disorder: Opioids

Substance use disorders (SUD), including the abuse of alcohol, prescription medications, or opioids, can lead to significant negative consequences to an individual's mental and physical health, work performance, housing status, and social functioning. Important issues being studied include alcohol screening and brief counseling, SUD specialty care, and the treatment of common comorbidities (i.e., SUD and PTSD or SUD and chronic pain).

Search results were generated based on the search term "Opioid". Results are updated weekly, as new data are available.

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(5 of more than 507 OPIOID focused publications)

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Publication Briefs

(5 of more than 33 OPIOID focused publication briefs)

  • Dual Use of VA and Medicare Associated with Substantial Increase in Risk of Potentially Unsafe Opioid Use among Veterans
    This study sought to estimate the prevalence and consequences of receiving prescription opioids from both VA and Medicare Part D for all dually-enrolled Veterans who filled a prescription opioid in either system in calendar year 2012. Findings showed that among Veterans dually enrolled in Medicare Part D and VA and receiving prescription opioids in 2012, more than 1 in 8 received opioids from both...
    Date: February 1, 2018
  • Medical Record Alert Associated with Reduced Opioid and Benzodiazepine Co-prescribing
    This implementation project evaluated the effectiveness of an advanced medication alert designed to reduce opioid and benzodiazepine co-prescribing among Veterans with high-risk conditions (substance use disorder, sleep apnea, suicide risk, and age =65) at one VA healthcare system (VA Puget Sound). Findings showed that the proportions of patients with concurrent prescriptions decreased significant...
    Date: December 28, 2017
  • Systematic Review: Patient Outcomes in Dose Reduction or Discontinuation of Long-term Opioid Therapy Suggest Utility of Multimodal Care
    Investigators examined the evidence on the effectiveness of strategies to reduce or discontinue long-term opioid therapy (LTOT) prescribed for chronic pain – and the effect of dose reduction or discontinuation on important patient outcomes, including pain severity and pain-related function. Findings showed that there are multiple strategies to reduce or discontinue long-term opioid treatment for c...
    Date: July 18, 2017
  • Higher Risk of Suicidal Ideation and Suicidal Self-Directed Violence following Discontinuation of Long-term Opioid Therapy
    The primary objective of this study was to identify predictors of suicidal ideation (SI) and non-fatal suicidal self-directed violence (SSV) following clinician-initiated discontinuation of long-term opioid therapy. Findings showed that a substantial proportion of Veterans with substance use disorder diagnoses and similar matched patients experienced suicidal ideation or suicidal self-directed vio...
    Date: July 1, 2017
  • Managing Chronic Pain in the Wake of the Opioid Backlash
    This JAMA Viewpoint commentary discusses several options for managing pain, as well as the overuse of the term “opioid epidemic.” Authors warn that imperfect treatments do not justify therapeutic distrust, and suggest that there is a broad menu of partially effective treatment options that can maximize the chances of achieving at least partial amelioration of patients’ chronic pain....
    Date: June 20, 2017

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( 5 of more than 32 OPIOID focused projects )

Project No.  Title  PI  Funding Start   
IIR 17-139 Cost Effectiveness of Interventions to Reduce Morbidity from Opioid Dependency Owens, Douglas 2018-04-01
IIR 16-145 Testing a Novel Strategy to Improve Implementation of Medication-Assisted Treatment for Veterans with Opioid Use Disorders in Low Performing Facilities Hagedorn, Hildi 2017-07-01
SDR 15-461 The Opioid Consent: Helping Optimize Information for Cancer and Effective (CHOICE) Pain Management Lorenz, Karl 2016-09-01
IIR 15-091 Use of a Prescription Drug Monitoring Program to Evaluate Concurrent VA and non-VA Opioid Prescriptions Carlson, Kathleen 2016-03-01
PPO 15-165 Spatiotemporal Analysis to Evaluate Opioid Safety Initiative Spread Miller, Donald 2016-03-01

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HSR&D Briefs, Reports, Newsletters

5 sample "Opioid" publications displayed.

  • Managing Chronic Pain
    ...Managing Chronic Pain Emerging Evidence Managing Chronic Pain VA/HSR&D researchers conduct an extensive number of investigations designed to improve...

  • August 2012 FORUM FY10. Opioids are considered a core pain management tool, but long-term effectiveness of opioid therapy for chronic pain is untested, and opioid...

  • Assessment and Management of Acute Pain in Adult Medical Inpatients
    ...outcomes or safety? For inpatients with dependencies on tobacco, alcohol, stimulant, marijuana, or opioids, how do differences in assessment and...

  • FORUM PDF format. 11-2016: Care Management 08-2016: Provider to Payer: Transforming VA Care 05-2016: Chronic pain, opioids 11-2015: Access 08-2015:...

  • Pain in Patients with Polytrauma
    ...used to reduce pain in these individuals (for example, oral opioids) have the potential to interfere with the active rehabilitation needed to...

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The most recent "Opioid" seminars are displayed.

Date Title Presenter(s)
2/6/2018 The VA Opioid Safety Initiative – how did we get here and what is ahead? Sandbrink, Friedhelm  
Moore, Von  
10/3/2017 Addressing Pain and Opioid Use Disorder in High Risk Patients Robeck, Ilene  
8/29/2017 Using VA Data to Inform the Design of Partnered Randomized Program Evaluations Minegishi, Taeko  
Garrido, Melissa  
7/26/2017 Opioid Dose Reduction in Patients Prescribed Long-term Opioid Therapy for Chronic Pain Lovejoy, Travis  
Becker, William  
5/2/2017 Patient Outcomes in Dose Reduction or Discontinuation of Long-Term Opioid Therapy: A Systematic Review Frank, Joseph  

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Other Resources

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