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Spotlight on Evidence Synthesis Program

Comparative Effectiveness of Smoking Cessation Treatments for Patients With Depression: A Systematic Review and Meta-analysis of the Evidence


by ,
Seminar date: 2/28/2011

Description: Tobacco smoking is the greatest preventable cause of disease in the U.S.. Smoking is disproportionately higher among persons with depression than the general population (45% vs. 22%), and smokers with depression may experience more challenges when trying to quit (e.g., higher nicotine dependence). While several evidence-based smoking cessation treatments are effective for the general population of smokers, the comparative effectiveness of these strategies in smokers with depression is uncertain. Investigators at the VA Evidence-Based Practice Center in Durham, NC conducted a systematic review of smoking cessation studies published through March, 2010 that resulted in 23 reports of 16 unique trials. Investigators reviewed these reports to answer five key questions.

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