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Spotlight on Evidence Synthesis Program

Using Comparative Effectiveness Review Findings in Practice: A new model


by Mark Helfand, MD, MS, MPH
Seminar date: 10/24/2013

Description: As clinicians, we want to base treatment decisions on all of the relevant clinical research data. Traditional systematic reviews, a key tool in evidence-based medicine, often rely on published articles that do not adequately represent all of the relevant information about a drug or device. This cyber seminar highlights a new appraisal method for evidence using the example of rhBMP-2, a biologic that has been used in lumbar spine surgery. It features two systematic reviews that were conducted as part of the Yale University Open Data Access project and published in a recent issue of the Annals of Internal Medicine and which received broad coverage in the media. A historic moment for open science: The Yale University Open Data Access Project and Medtronic. Annals of Internal Medicine, June 18, 2013, Volume 158, Number 12, pp 910-912.

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