Posttraumatic stress disorder (PTSD) is the emotional disorder most frequently associated with
combat and other potentially traumatic experiences that may occur during military service. It is
often chronic and may be associated with significant comorbidities and functional impairments.
Current first-line PTSD therapies include trauma-focused cognitive behavioral psychotherapies,
stress inoculation training, and pharmacotherapies. Complementary and alternative medicine
(CAM) interventions include a range of therapies that are not considered standard to the practice
of medicine in the U.S. CAM therapies are widely used by mental health consumers, including
Veterans, and numerous stakeholders have expressed strong interest in fostering the evidence
base for these approaches in PTSD. Thus, this evidence synthesis was requested by VA Research
and Development to inform decisions on the need for research in this area.