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Evidence Brief: Use of Intradialytic Parenteral Nutrition (IDPN) to Treat Malnutrition in Hemodialysis Patients

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Use of Intradialytic Parenteral Nutrition (IDPN) to Treat Malnutrition in Hemodialysis Patients

Investigators: Johanna Anderson, MPH; Kim Peterson, MS; Donald Bourne, MPH; Erin Boundy, MS

Evidence-based Synthesis Program (ESP) Coordinating Center, Portland VA Health Care System, Portland, OR

Washington (DC): Department of Veterans Affairs; March 2018.



Download PDF: Brief, Supplemental Materials

Background

The ESP Coordinating Center (ESP CC) is responding to a request from the Veterans Affairs Renal Field Advisory Committee for an evidence brief on the use of Intradialytic Parenteral Nutrition (IDPN) for the treatment of malnutrition among hemodialysis patients. Findings from this evidence brief will be used to develop recommendations on the use of IDPN in the treatment of Veteran hemodialysis patients with malnutrition.

Key Questions

Key Question 1: What is the effectiveness of IDPN for the treatment of malnutrition in hemodialysis patients?

Key Question 2: What are the potential adverse effects of using IDPN for the treatment of malnutrition in hemodialysis patients?

Key Question 3: What is the cost-effectiveness of using IDPN for the treatment of malnutrition in hemodialysis patients?

Key Question 4: Do the effectiveness and potential adverse effects of IDPN differ per patient characteristics (eg, patient demographics, comorbidities, disease severity)?

See also

Evidence Brief: Treatment for Malnutrition in Hemodialysis Patients (Management eBrief)

Anderson J, Peterson K, Bourne D, and Boundy E. Effectiveness of Intradialytic Parenteral Nutrition in Treating Protein-Energy Wasting in Hemodialysis: A Rapid Systematic Review. Journal of Renal Nutrition. 2019;29(5):361-369. doi: https://doi.org/10.1052/j.jrn.2018.11.009