Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government

VA Health Systems Research

Go to the VA ORD website
Go to the QUERI website

Cost-effectiveness of Leg Bypass versus Endovascular Therapy for Critical Limb Ischemia: A Systematic Review

Click for list of published reports
Click for topic nomination form
Click for list of reports in progress

Subscribe to the
ESP Report RSS feed RSS feed icon
Systematic Review - Cost-effectiveness of Leg Bypass versus Endovascular Therapy for Critical Limb Ischemia: A Systematic Review

Prepared by:
Evidence Synthesis Program (ESP) Center West Los Angeles VA Medical Center Los Angeles, CA
Paul G. Shekelle, MD, PhD, Director

Recommended citation:
Childers C, Lamaina M, Liu C, Mak S, Booth M, Gibbons M, Shekelle PG. Cost-effectiveness of Leg Bypass versus Endovascular Therapy for Critical Limb Ischemia. Washington, DC: Evidence Synthesis Program, Health Services Research and Development Service, Office of Research and Development, Department of Veterans Affairs.VA ESP Project#05-226; 2019.

Download PDF: Complete Report, Executive Summary, Report, Appendices

Introduction

Critical limb ischemia (CLI) is a severe form of peripheral arterial disease (PAD) marked by ischemic rest pain, tissue loss, or gangrene. CLI is associated with significant morbidity, mortality, and resource utilization. Patients can be treated with revascularization, either surgical or endovascular. To help clinicians, patients, and policymakers decide between surgery-first and endovascular-first approaches in patients with CLI, we were asked to conduct a systematic review of the literature.

Key Questions

KQ1: Among adults with CLI, what is the cost-effectiveness of leg bypass compared to endovascular procedures including balloon angioplasty, arterial stents, and atherectomy?

KQ2: Does the cost-effectiveness of leg bypass compared to endovascular procedures for CLI vary by patient population, setting, or time (short vs long-term)?

See also

Cost-Effectiveness of Leg Bypass versus Endovascular Therapy for Critical Limb Ischemia (Management eBrief)

Cost-effectiveness of Leg Bypass versus Endovascular Therapy for Critical Limb Ischemia (Cyberseminar)

Lamaina M, Childers CP, Liu C, et al. Clinical Effectiveness and Resource Utilization of Surgery versus Endovascular Therapy for Chronic Limb-Threatening Ischemia. Annals of Vascular Surgery. Published online May 19, 2020. DOI: 10.1016/j.avsg.2020.04.043


Questions about the HSR website? Email the Web Team

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.