Prepared by: Evidence Synthesis Program (ESP) Coordinating Center
Portland VA Health Care System
Mark Helfand, MD, MPH, MS, Director
Recommended Citation: Anderson J, Parr NJ, Vela K. Evidence Brief: Transcranial Magnetic Stimulation (TMS) for Chronic Pain, PTSD, TBI, Opioid Addiction, and Sexual Trauma. VA ESP Project #09-009; 2020.
The ESP Coordinating Center (ESP CC) is responding to a request from the Center for Compassionate Care Innovation for an evidence brief on the use of transcranial magnetic stimulation (TMS) for the treatment of mental and physical health diagnoses (not including major depressive disorder). Findings from this evidence brief will be used to inform a VHA pilot program to provide access to TMS for Veterans suffering from chronic pain, post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), opioid addiction, or sexual trauma as required by HR 1162, "No Hero Left Untreated Act".
Key Question 1: What is the effectiveness of TMS for the treatment of post-traumatic stress disorder, traumatic brain injury, sexual trauma, chronic pain, or opioid addiction?
Key Question 2: What are the potential adverse effects of using TMS for the treatment of post-traumatic stress disorder, traumatic brain injury, sexual trauma, chronic pain, or opioid addiction?
Key Question 3: Do the effectiveness and potential adverse effects of TMS differ according to patient or intervention characteristics (eg, patient demographics, comorbidities, disease severity, TMS frequency)?