Health Services Research & Development

Veterans Crisis Line Badge
Go to the ORD website
Go to the QUERI website

HSR&D Citation Abstracts

Search | Search by Center | Search by Source | Keywords in Title

Blalock DV, Bosworth HB, Reeve BB, Voils CI. Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia. Journal of behavioral medicine. 2019 Apr 1; 42(2):291-299.
PubMed logo Search for Abstract from PubMed
(This link leaves the website of VA HSR&D.)

Abstract: Medication nonadherence is a significant clinical problem among individuals taking statins. Poor adherence is often attributable to several reasons, yet most adherence interventions target a single reason. Baseline data were examined from a randomized clinical trial of 236 patients with hyperlipidemia. A latent class analysis was then performed on patients reporting any nonadherence (n?=?109). A 4-class solution provided the most optimal fit and differentiation of classes. Class 1 (N?=?59, 54%) included patients who reported occasionally forgetting. Class 2 (N?=?16, 14%) represented patients who were concerned about side effects. Class 3 (N?=?17, 16%) represented patients who reported out-of-routine life events as contributing to nonadherence. Class 4 (N?=?17, 16%) represented patients who endorsed a large number reasons indiscriminately. Class membership was almost uniformly unrelated to any patient demographic factors or treatment arm. Each cluster of reasons defining these patients may be best addressed through different intervention strategies.