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Barshes NR, Mindru C, Trautner BW, Rodriguez-Barradas MC. Discordant isolates in bone specimens from patients with recurrent foot osteomyelitis. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2019 Apr 1; 38(4):767-769.
We compared paired operative bone cultures (initial operation and reoperation) for 35 patients who experienced foot osteomyelitis treatment failure at a single hospital. Concordance was poor (kappa? = 0.180). Staphylococcus aureus, gram negatives, and anaerobes were the most common discordant bacteria seen at reoperation, while Enterococcus was the most persistent.