The Science of Precision Prevention: Research Opportunities and Clinical Applications to Reduce Cardiovascular Health Disparities.

Pearson TA, Vitalis D, Pratt C, Campo R, Armoundas AA, Au D, Beech B, Brazhnik O, Chute CG, Davidson KW, Diez-Roux AV, Fine LJ, Gabriel D, Groenveld P, Hall J, Hamilton AB, Hu H, Ji H, Kind A, Kraus WE, Krumholz H, Mensah GA, Merchant RM, Mozaffarian D, Murray DM, Neumark-Sztainer D, Petersen M, Goff D. The Science of Precision Prevention: Research Opportunities and Clinical Applications to Reduce Cardiovascular Health Disparities. JACC. Advances. 2024 Jan 1; 3(1).

Related HSR&D Project(s)

• RCS 21-135 – Research Career Scientist Award

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Abstract:

Precision prevention embraces personalized prevention but includes broader factors such as social determinants of health to improve cardiovascular health. The quality, quantity, precision, and diversity of data relatable to individuals and communities continue to expand. New analytical methods can be applied to these data to create tools to attribute risk, which may allow a better understanding of cardiovascular health disparities. Interventions using these analytic tools should be evaluated to establish feasibility and efficacy for addressing cardiovascular disease disparities in diverse individuals and communities. Training in these approaches is important to create the next generation of scientists and practitioners in precision prevention. This state-of-the-art review is based on a workshop convened to identify current gaps in knowledge and methods used in precision prevention intervention research, discuss opportunities to expand trials of implementation science to close the health equity gaps, and expand the education and training of a diverse precision prevention workforce.