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Harvey, Abdulkerim, Strymish, Ryan, Boudreau, Gifford, Hyde, Branch-Elliman. Infectious Complications of Substance Use: A Retrospective Cohort Study of Hospitalized Veterans. Open forum infectious diseases. 2025 Jun 1; 12(6):ofaf301, DOI: 10.1093/ofid/ofaf301.
Invasive bacterial infections (IBI) associated with drug use are increasing, but the full disease burden remains unknown. We characterized national trends in the prevalence of IBI among veterans with evidence of substance use using a large, national cohort. High rates of IBI highlight a need for more comprehensive infection reduction strategies, including emphasis on gram-negative infections.