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Keaton D, Lamkin N, Cassidy KA, Meyer WJ, Ignacio RV, Aulakh L, Blow FC, Sajatovic M. Utilization of herbal and nutritional compounds among older adults with bipolar disorder and with major depression. International journal of geriatric psychiatry. 2009 Oct 1; 24(10):1087-93.
Orally ingested HNC was used by nearly one in three older adults with mood disorders, and was more common among those with bipolar disorder compared to those with major depression. Most individuals did not discuss HNC use with their physicians. Clinicians need to assess for HNC use, particularly with respect to potential drug-drug interactions.