Infectious Disease: Hepatitis C
Infectious diseases can be acquired from another person, through exposure to an infected environment, or via an animal or insect bite. Important issues being studied include the prevention, detection, and treatment of hepatitis C virus (HCV), human immunodeficiency virus (HIV), influenza, methicillin-resistant Staphylococcus aureus (MRSA) and other hospital-associated infections (HAIs), and pneumonia.
Search results were generated based on the search term "Hepatitis". Results are updated weekly, as new data are available.
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(5 of more than 454 HEPATITIS focused publications)
- Chhatwal J, Samur S, Bethea ED, Ayer T, Kanwal F, Hur C, Roberts MS, Terrault N, Chung RT. Transplanting hepatitis C virus-positive livers into hepatitis C virus-negative patients with preemptive antiviral treatment: A modeling study. Hepatology (Baltimore, Md.). 2018 Jun 1; 67(6):2085-2095.
- Shah R, Ho EY, Kramer JR, Richardson P, Sansgiry S, El-Serag HB, Hou JK. Hepatitis B Virus Screening and Reactivation in a National VA Cohort of Patients with Inflammatory Bowel Disease Treated with Tumor Necrosis Factor Antagonists. Digestive diseases and sciences. 2018 Jun 1; 63(6):1551-1557.
- Hsu YC, Ho HJ, Lee TY, Huang YT, Wu MS, Lin JT, Wu CY, El-Serag HB. Temporal trend and risk determinants of hepatocellular carcinoma in chronic hepatitis B patients on entecavir or tenofovir. Journal of Viral Hepatitis. 2018 May 1; 25(5):543-551.
- Hsu YC, Yip TC, Ho HJ, Wong VW, Huang YT, El-Serag HB, Lee TY, Wu MS, Lin JT, Wong GL, Wu CY. Development of a scoring system to predict hepatocellular carcinoma in Asians on antivirals for chronic hepatitis B. Journal of Hepatology. 2018 Aug 1; 69(2):278-285.
- Benhammou JN, Dong TS, May FP, Kawamoto J, Dixit R, Jackson S, Dixit V, Bhattacharya D, Han SB, Pisegna JR. Race affects SVR12 in a large and ethnically diverse hepatitis C-infected patient population following treatment with direct-acting antivirals: Analysis of a single-center Department of Veterans Affairs cohort. Pharmacology research & perspectives. 2018 Apr 1; 6(2):e00379.
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(5 of more than 21 HEPATITIS focused publication briefs)
- VA Successfully Implements Interferon-free Treatment for Hepatitis C Virus in Previously Undertreated Patient Populations
This study examined the adoption of interferon-free treatment for hepatitis C virus (HCV) in VA to learn who received this therapy and whether the limitations of interferon-containing treatments have been overcome, including low rates of use among VA healthcare users who are African American or Hispanic, and among those with HCV-HIV co-infection. Findings showed that with the advent of interferon-...
Date: March 7, 2018
- HCV-Related Complications Increasing among Women Veterans
This study examined gender-related differences in the incidence and prevalence of cirrhosis, decompensated cirrhosis, and hepatocellular cancer (HCC) between 2000 and 2013. Findings showed that the incidence and prevalence of hepatitis C virus (HCV) complications was higher in men than in women. However, the rate of increase in the incidence rates of cirrhosis and decompensated cirrhosis among HCV...
Date: November 1, 2017
- Direct-Acting Antiviral Agents Reduce Risk of Hepatocellular Cancer among Veterans with Hepatitis C
This study examined the risk of hepatocellular cancer (HCC) following sustained virological response (SVR) among 22,500 Veterans with hepatitis C virus (HCV) who received directing-acting antivirals (DAA) treatment at any of 129 VA hospitals between January and December 2015. Findings showed that in Veterans treated with DAAs, SVR was associated with a 76% reduction in the risk of developing hepat...
Date: October 1, 2017
- VA Hepatitis C Care and Experiences with the Choice Program
This study examined perspectives and experiences with the VA Choice Program among Veterans with HCV and their providers at three VAMCs in the New England region. Findings showed that the Choice Program has the potential to increase Veterans’ access to hepatitis C virus (HCV) treatment, but Veterans and VA providers described substantial problems in the initial years of the program. Four main theme...
Date: March 3, 2017
- Engagement in Hepatitis C Virus Care among Homeless and non-Homeless VA Patients
This study sought to describe engagement in hepatitis C virus (HCV) care among homeless and non-homeless Veterans in the new era of HCV treatment, which includes direct-acting agents (DAAs) with shorter treatment durations, fewer side effects, and higher sustained virologic response (SVR) rates than the older treatment regimens. Findings showed that VA providers do a better job of testing for and ...
Date: March 1, 2017
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( 5 of more than 32 HEPATITIS focused projects
|| Advanced Prediction Models to Optimize Treatment and Access for Veterans with Hepatitis C
|| Quality of Care for Hepatitis C in Veterans Who Are Homeless
|| Care for Women Veterans with Hepatitis C Virus Infection
|| Web-based Intervention to Reduce Alcohol Use in Veterans with Hepatitis C
|| Cost-effective Uses of New Hepatitis C Treatments and their VA Budgetary Impact
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