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CDA 13-021 – HSR&D Study

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CDA 13-021
Implementation research of benefit-based treatment for cardiovascular disease
Jeremy B. Sussman MD MS
VA Ann Arbor Healthcare System, Ann Arbor, MI
Ann Arbor, MI
Funding Period: January 2015 - December 2019




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Journal Articles

  1. Prescott HC, Sussman JB, Wiersinga WJ. Postcritical illness vulnerability. Current opinion in critical care. 2020 Oct 1; 26(5):500-507.
  2. Johansen ME, Niforatos JD, Sussman JB. The Ecology of Antihypertensives in the United States, 1997-2017. Journal of general internal medicine. 2021 Mar 1; 36(3):699-704.
  3. Levine DA, Gross AL, Briceño EM, Tilton N, Kabeto MU, Hingtgen SM, Giordani BJ, Sussman JB, Hayward RA, Burke JF, Elkind MSV, Manly JJ, Moran AE, Kulick ER, Gottesman RF, Walker KA, Yano Y, Gaskin DJ, Sidney S, Yaffe K, Sacco RL, Wright CB, Roger VL, Allen NB, Galecki AT. Association Between Blood Pressure and Later-Life Cognition Among Black and White Individuals. JAMA neurology. 2020 Jul 1; 77(7):810-819.
  4. Zheutlin AR, Niforatos JD, Stulberg E, Sussman JB. Failure of Cardiovascular Phase 3 Randomized Clinical Trials to Report Pre-trial and Post-trial Parameters: a Cross-sectional Analysis of Journal of general internal medicine. 2020 Jun 24.
  5. Sussman JB, Holleman RG, Youles B, Lowery JC. Correction to: Quality Improvement and Personalization for Statins: the QUIPS Quality Improvement Randomized Trial of Veterans' Primary Care Statin Use. Journal of general internal medicine. 2020 Jan 2.
  6. Sussman JB, Murthy VL. The Impact of Age on the Likely Impact of Coronary Calcium Testing in the 2018 Cholesterol Guidelines. Journal of general internal medicine. 2020 Jan 1; 35(1):386-388.
  7. Basu S, Yudkin JS, Kehlenbrink S, Davies JI, Wild SH, Lipska KJ, Sussman JB, Beran D. Estimation of global insulin use for type 2 diabetes, 2018-30: a microsimulation analysis. The lancet. Diabetes & endocrinology. 2019 Jan 1; 7(1):25-33.
  8. Berkowitz SA, Sussman JB, Jonas DE, Basu S. Generalizing Intensive Blood Pressure Treatment to Adults With Diabetes Mellitus. Journal of the American College of Cardiology. 2018 Sep 11; 72(11):1214-1223.
  9. Yadlowsky S, Hayward RA, Sussman JB, McClelland RL, Min YI, Basu S. Clinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk. Annals of internal medicine. 2018 Jul 3; 169(1):20-29.
  10. DeJonckheere M, Robinson CH, Evans L, Lowery J, Youles B, Tremblay A, Kelley C, Sussman JB. Designing for Clinical Change: Creating an Intervention to Implement New Statin Guidelines in a Primary Care Clinic. JMIR human factors. 2018 Apr 24; 5(2):e19.
  11. Basu S, Sussman JB, Berkowitz SA, Hayward RA, Bertoni AG, Correa A, Mwasongwe S, Yudkin JS. Validation of Risk Equations for Complications of Type 2 Diabetes (RECODe) Using Individual Participant Data From Diverse Longitudinal Cohorts in the U.S. Diabetes Care. 2018 Mar 1; 41(3):586-595.
  12. Markovitz AA, Holleman RG, Hofer TP, Kerr EA, Klamerus ML, Sussman JB. Effects of Guideline and Formulary Changes on Statin Prescribing in the Veterans Affairs. Health services research. 2017 Dec 1; 52(6):1996-2017.
  13. Basu S, Sussman JB, Rigdon J, Steimle L, Denton BT, Hayward RA. Benefit and harm of intensive blood pressure treatment: Derivation and validation of risk models using data from the SPRINT and ACCORD trials. PLoS Medicine. 2017 Oct 1; 14(10):e1002410.
  14. Maciejewski ML, Mi X, Sussman J, Greiner M, Curtis LH, Ng J, Haffer SC, Kerr EA. Overtreatment and Deintensification of Diabetic Therapy among Medicare Beneficiaries. Journal of general internal medicine. 2018 Jan 1; 33(1):34-41.
  15. Sussman JB, Wiitala WL, Zawistowski M, Hofer TP, Bentley D, Hayward RA. The Veterans Affairs Cardiac Risk Score: Recalibrating the Atherosclerotic Cardiovascular Disease Score for Applied Use. Medical care. 2017 Sep 1; 55(9):864-870.
  16. Basu S, Sussman JB, Hayward RA. Detecting Heterogeneous Treatment Effects to Guide Personalized Blood Pressure Treatment: A Modeling Study of Randomized Clinical Trials. Annals of internal medicine. 2017 Mar 7; 166(5):354-360.
  17. Zawistowski M, Sussman JB, Hofer TP, Bentley D, Hayward RA, Wiitala WL. Corrected ROC analysis for misclassified binary outcomes. Statistics in medicine. 2017 Jun 15; 36(13):2148-2160.
  18. Govani SM, Wiitala WL, Stidham RW, Saini SD, Hou JK, Feagins LA, Sussman JB, Higgins PD, Waljee AK. Age Disparities in the Use of Steroid-sparing Therapy for Inflammatory Bowel Disease. Inflammatory Bowel Diseases. 2016 Aug 1; 22(8):1923-8.
  19. Basu S, Yudkin JS, Sussman JB, Millett C, Hayward RA. Alternative Strategies to Achieve Cardiovascular Mortality Goals in China and India: A Microsimulation of Target- Versus Risk-Based Blood Pressure Treatment. Circulation. 2016 Mar 1; 133(9):840-8.
  20. Sussman JB, Kerr EA, Saini SD, Holleman RG, Klamerus ML, Min LC, Vijan S, Hofer TP. Rates of Deintensification of Blood Pressure and Glycemic Medication Treatment Based on Levels of Control and Life Expectancy in Older Patients With Diabetes Mellitus. JAMA internal medicine. 2015 Dec 1; 175(12):1942-9.
  21. Iwashyna TJ, Burke JF, Sussman JB, Prescott HC, Hayward RA, Angus DC. Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care. American journal of respiratory and critical care medicine. 2015 Nov 1; 192(9):1045-51.
  22. Bradley SM, Hess E, Winchester DE, Sussman JB, Aggarwal V, Maddox TM, Barón AE, Rumsfeld JS, Ho PM. Stress Testing After Percutaneous Coronary Intervention in the Veterans Affairs HealthCare System: Insights from the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program. Circulation. Cardiovascular quality and outcomes. 2015 Sep 1; 8(5):486-92.
  23. Elmunzer BJ, Singal AG, Sussman JB, Deshpande AR, Sussman DA, Conte ML, Dwamena BA, Rogers MA, Schoenfeld PS, Inadomi JM, Saini SD, Waljee AK. Comparing the effectiveness of competing tests for reducing colorectal cancer mortality: a network meta-analysis. Gastrointestinal endoscopy. 2015 Mar 1; 81(3):700-709.e3.
Journal Other

  1. Sussman JB, Heisler M. Of Barbershops and Churches. [Editorial]. Circulation. Cardiovascular quality and outcomes. 2018 Oct 1; 11(10):e005149.
  2. Hofer TP, Sussman JB, Hayward RA. New Studies Do Not Challenge the American College of Cardiology/American Heart Association Lipid Guidelines. Annals of internal medicine. 2016 May 17; 164(10):683-4.
Online News Media Articles

  1. Sussman JB, Kerr EA. Many seniors may be overtreated for T2DM, hypertension. Physician's Briefing [Internet]. 2015 Oct 20. Available from:

DRA: Cardiovascular Disease, Aging, Older Veterans' Health and Care
DRE: Technology Development and Assessment
Keywords: Practice Patterns/Trends
MeSH Terms: none

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