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Murthy SB, Jawaid A, Qureshi SU, Kalkonde Y, Wilson AM, Johnson ML, Kunik ME, Schulz PE. Does diabetes mellitus alter the onset and clinical course of vascular dementia? Behavioural Neurology. 2010 Jan 1; 23(3):145-51.
A history of pre-morbid DM was associated with an earlier onset and faster cognitive deterioration in VaD. Moreover, DM was associated with neuropsychiatric symptoms in patients with VaD. A larger study is needed to verify these associations. It will be important to investigate whether better glycemic control will mitigate the potential effects of DM on VaD.