Human Immunodeficiency Virus (HIV)
Human immunodeficiency virus (HIV) is an infectious disease that attacks the human body’s immune system. If left untreated, the virus can lead to acquired immunodeficiency syndrome (AIDS). Over time, HIV destroys CD4 cells, a key infection-fighting cell. Without a sufficient number of CD4 cells, the immune system becomes weakened and can no longer effectively fight off infections. Within VA, HIV research focuses on testing, prevention, and delivery of care to Veterans with HIV.
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(5 of more than 1468 HIV focused publications)
- Keddem S, Dichter ME, Hamilton AB, Chhatre S, Sonalkar S. Awareness of HIV Preexposure Prophylaxis Among People at Risk for HIV: Results From the 2017-2019 National Survey of Family Growth. Sexually Transmitted Diseases. 2021 Dec 1; 48(12):967-972.
- Akgün KM, Krishnan S, Butt AA, Gibert CL, Graber CJ, Huang L, Pisani MA, Rodriguez-Barradas MC, Hoo GWS, Justice AC, Crothers K, Tate JP. CD4+ cell count and outcomes among HIV-infected compared with uninfected medical ICU survivors in a national cohort. AIDS (London, England). 2021 Nov 15; 35(14):2355-2365.
- Hanberg JS, Hsieh E, Akgün KM, Weinstein E, Fraenkel L, Justice AC, VACS Project Team. Incident Rheumatoid Arthritis in HIV Infection: Epidemiology and Treatment. Arthritis & rheumatology (Hoboken, N.J.). 2021 Dec 1; 73(12):2189-2199.
- McClure JB, Catz SL, Chalal C, Ciuffetelli R, Coggeshall S, DeFaccio RJ, Fleehart S, Heffner JL, Thompson E, Williams EC, Crothers K. Design and methods of a randomized trial testing the novel Wellness Intervention for Smokers Living with HIV (WISH). Contemporary clinical trials. 2021 Nov 1; 110:106486.
- Woods SP, Babicz MA, Matchanova A, Sullivan KL, Avci G, Hasbun R, Giordano TP, Fazeli P, Morgan EE. A Clinical Pilot Study of Spaced Retrieval Practice with a Self-Generation Booster to Improve Health-Related Memory in Persons With HIV Disease. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. 2021 Oct 13; 36(7):1296-1306.
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(5 of more than 22 HIV focused publication briefs)
- VA Successfully Implements Interferon-free Treatment for Hepatitis C Virus in Previously Undertreated Patient Populations
This study examined the adoption of interferon-free treatment for hepatitis C virus (HCV) in VA to learn who received this therapy and whether the limitations of interferon-containing treatments have been overcome, including low rates of use among VA healthcare users who are African American or Hispanic, and among those with HCV-HIV co-infection. Findings showed that with the advent of interferon-...
Date: March 7, 2018
- Evidence Review Identifies Modest Mortality Disparities among Racial and Ethnic Minority Groups in VA Healthcare
To support VA’s efforts to better understand the scale and determinants of disparities in racial and ethnic mortality – and to develop interventions to reduce disparities, investigators from the VA Evidence-based Synthesis Program (ESP) Coordinating Center in Portland, OR conducted an evidence review of mortality disparities specific to VA. Findings showed that although VA’s equal access healthcar...
Date: March 1, 2018
- Racial Disparities in HIV Quality of Care that May Extend to Common Comorbid Conditions
To more fully understand patterns of racial disparities in the quality of care for persons with HIV infection, this study examined a national cohort of Veterans in care for HIV in the VA healthcare system during 2013. Findings showed that racial disparities were identified in quality of care specific to HIV infection – and in the care of common comorbid conditions. Blacks were less likely than whi...
Date: September 22, 2016
- New Guidelines May Significantly Decrease Cost for Testing Immune Function in Veterans with HIV
In 2012, the Department of Health and Human Services recommended CD4 testing in patients with HIV every 3 to 6 months – except in patients with consistently suppressed virus and sustained CD4 cell count, who could be tested every 6 to 12 months. In 2014, updated guidelines recommended that in individuals with viral suppression, CD4 testing be considered either optional or annual, depending on the ...
Date: July 1, 2016
- Consequences of Notifying VA Patients about Potential Exposure to Large-Scale Adverse Events
This study sought to determine the intended and unintended consequences of patient notification following a large-scale adverse event (LSAE) within the VA healthcare system, which systematically looks for LSAEs, tracks potentially exposed patients, and communicates with them after LSAE notification. Findings showed that more than two-thirds of potentially exposed patients returned for HCV, HBV, an...
Date: May 1, 2015
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( 5 of more than 79 HIV focused projects
|| A nurse-led intervention to extend the Veteran HIV treatment cascade for cardiovascular disease prevention (V-EXTRA-CVD)
|| HIV Translating Initiatives for Depression into Effective Solutions – Hyb
|| A Personalized mHealth Approach to Smoking Cessation for Veterans Living with HIV
|| A Patient-centered Approach to Comorbidity Management in Aging Veterans with HIV
|| Effectiveness of Telehealth Collaborative Care for Veterans with HIV in Ruraland Outlying Settings
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